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Interestingly, we found that ORF3a showed a puncta-like distribution in transfected cells, and some ORF3a was colocalized with LAMP1, a lysosome membrane marker protein (Fig

Potential therapeutic strategies are also considered, including metabolic inhibitors and nanocarriers capable of crossing the blood-brain barrier (BBB) to restore metabolic and epigenetic balance

Phosphorylation of p27Kip1 by Epstein-Barr virus protein kinase induces its degradation through SCFSkp2 ubiquitin ligase actions during viral lytic replication

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