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With enormous diversity in chemical and physiological properties, these molecules serve a wide variety of purposes, including as important components of the bacterial cell envelope 7,30,34 , providing protection against desiccation and toxic substances 87,88,89 , mediating attachment to surfaces 87,90 , biofilm formation 91,92 , host interaction 93,94 , and bacterial motility 58,60

76 Activated PKC and PKC recruit caspase recruitment domain family member 11 (CARMA1), B cell leukemia/lymphoma 10 (Bcl-10), and MALT1 paracaspase (MALT1), and the complex composed of CARMA1/BCL-10/MALT1 was found to be active in NF-B and c -Jun N-terminal kinase (JNK) signaling, which mediates immune cell activation, proliferation, and differentiation, and its aberrant expression has been associated with autoimmune diseases and lymphoma formation

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PK generated all Fig.s

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