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Moreover, all of the simulated dosing scenarios resulted in C MAX and AUC of primaquine in infants well-below that of the reference threshold observed in mothers receiving a single low dose of primaquine

We also confirmed that there were no defects in the early differentiation process into endoderm by performing quantitative RT-PCR at Day 5 of differentiation for relevant markers ( CXCR4, FOXA2, SOX17 ) 42 (Supplementary Fig