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Regulatory Status and Research Context AOD-9604 is not FDA-approved for any therapeutic indication

Although the gut microbiota is well established in providing the host with protection against foreign pathogens, primarily by resisting intestinal colonisation by enteric pathogens, translocation of these microbes across the gut barrier can occur via various mechanisms and often results in undesirable outcomes for the host (Mainous et al

Drug repurposing is the best approach to recognize therapeutic options for COVID19 in a limited time [14, 15]

The area postrema lacks a specific bloodbrain diffusion barrier to large polar molecules and is therefore anatomically positioned to detect the chemical milieu of the blood

doi: 10.1007/s00109-010-0607-4