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Another study found that N-acetylcarnosine decreased lens cell telomere shortening to protect against oxidative stress (75,136) and the harmful effects of lipid peroxides on the crystalline lens in vivo (137)

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

An initiator and rate-limiting enzyme, ODC is a pyridoxal-5-phosphate-dependent enzyme

Chiang S, Kovacevic Z, Sahni S, Lane DJ, Merlot AM, Kalinowski DS, Huang ML, Richardson DR

Overall, targeting mitophagy in PDAC holds promise, but clinical translation will require pathway-specific insights, selective modulators, advanced delivery strategies, and effective patient stratification