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Stress Reporter Assay of AQ-QI and DEAQ-QI To identify the stress response pathways upon AQ-QI and DEAQ-QI exposure, oxidative stress response (SRXN1-GFP), ER stress response (CHOP-GFP), inflammation response (ICAM1-GFP), and DNA damage response (p21-GFP) pathways were measured with a high-content image-based BAC-GFP stress responses reporter assay (Wink et al., 2014, 2017)

Parisi S, Ditto MC, Ghellere F, Panaro S, Piccione F, Borrelli R, et al

The study was supported by the Deutsche Forschungsgemeinschaft (Grant BE 1540/11-1 to K.B.)

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They exist in a regulatory gray area, available for research purposes but not sanctioned for medical treatment