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It was proved that the melatonin has an in vitro lipidic peroxidation inhibiting effect, and so being adopted as reference

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Shimano et al., 1999) and reduced AKT-mediated phosphorylation (Migita et al., 2008) inhibiting lipid synthesis

2.7 GPX7 Glutathione peroxidase 7 (GPX7) is a non-selenocysteine active neutral antioxidant enzyme in mammals, also known as non-selenium cysteine phGPX (NPGPX) due to its homology to phospholipid peroxide GPX (phGPX = GPX4) ( E

This aversive reaction creates a pharmacological deterrent to drinking