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Evolutionary Action Score of TP53 Analysis in Pathologically High-Risk Human Papillomavirus-Negative Head and Neck Cancer From a Phase 2 Clinical Trial: NRG Oncology Radiation Therapy Oncology Group 0234

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We first outline the core molecular machinery of ferroptosis, focusing on the interplay between iron homeostasis, lipid peroxidation, the GPX4glutathione axis, and recently identified defense pathways