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Fetal bradycardia may occur in 20 to 30 percent of patients receiving paracervical nerve block anesthesia with the amide-type local anesthetics and may be associated with fetal acidosis

doi:10.1096/fj.02-0847fje

Taken together, these converging lines of evidence reinforce a central conclusion: No single modality can sufficiently capture the complexity of neurodegeneration or reliably measure neuroprotection in humans