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Although various carriers have been exploited for delivery of neurotherapeutics, target-orientated nanotherapeutic delivery is more precise for brain targeting

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Elevated cortisol levels affect gastrointestinal function through several mechanisms: inhibiting gut motility, reducing intestinal blood flow, impairing gut barrier integrity, altering gut microbiota composition, and increasing visceral hypersensitivity (Vanuytsel et al., 2014)