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Misfolded proteins are retained and refolded in the ER, and terminally misfolded proteins are retrotranslocated to the cytosol, and degraded by the ubiquitinproteasome system 3,4

They protect the liver from oxidative damage and environmental stressors, supporting long-term liver health

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This multidimensional strategy aims to concurrently ameliorate motor and non-motor symptoms, balance short-term symptomatic control with long-term disease modification, thereby delaying disease progression and comprehensively improving patients' quality of life

Soleimani serves as the lead principal investigator on multiple projects focused on the application of AI in infectious keratitis and ocular surface diseases to advance diagnosis and management.