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The advancement of disease-modifying therapies for PD hinges on continuous research aimed at deepening the mechanistic understanding of the Nrf2NLRP3 axis and refining pharmacological strategies

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At the same time, the study also found that Polyphyllin III treatment induced a protective upregulation of xcT, a negative regulator of ferroptosis

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Jun 7 2017;18(6)doi:10.3390/ijms18061221

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