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In contrast, the corresponding residue of L142 in the D14 group was the highly conserved V143 ShD14 (Supplementary Figs

By Feb 2023, 20 patients had developed HCC and they were all early stage disease

doi: 10.3892/or.2018.6798 148 ChenMXWangSYKuoCHTsaiIL

Bnger, M., de Groot, P

Third, not all POIs are equally amenable to CRBN- or VHL-based degraders, possibly due to incompatibilities in surface topologies and hence an inability to form a productive ternary complex 21,22,23