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The slower formation rate of 7 from Ser, relative to that of 1 from Cys, correlates with the higher pKa value of the serinyl hydroxyl group (predicted at 13.4 (ACD/I-Lab, 5.0.0.184, Advanced Chemistry Development, Inc., Toronto, ON, Canada, www.acdlabs.com, (2019)) compared to the cysteinyl thiol group (~8.4 (AAs and acidity values, (accessed 1 May 2019)), suggesting hydroxyl/thiol deprotonation might be (partially) rate limiting 39

Axonal regeneration was induced by adding 1 nM of EpoB (from Sorangium cellulosum

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These isotopes of iodine emit, primarily, beta radiation (that travel short distances in tissues) and gamma radiation (that can penetrate the entire body)

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