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Activated PXR in transgenic female mice resulted in a heightened sensitivity to an oxidative toxicant [25]

Detoxification: Oxygen is essential for the breakdown and elimination of toxins and waste products through processes such as oxidation and hydroxylation

The same as related factors in the Wnt signaling pathway, expression levels of related factors in the BMP signaling pathway, such as BMP2 , BMP4 , BMP7 , and Samd2 , and expression levels of other related factors, such as FGF7 , CYP17 , CXCL13 , EDAR , TGF2 , PI3KB , and Akt , were also comparable

International standard preparations (for example, for human growth hormone) are established by WHO experts (National Institute for Biological Standards and Control (NIBSC))

PMID: 15712276