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O'Rourke, E

4.1.5 Targeting ferroptosis to improve renal fibrosis in DN Studies indicate that ferroptosis is involved in renal fibrosis in DN, which is the final pathological change in DN (130)

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Administration of BmK IT2 markedly prolonged the latency to SE onset, attenuated SE severity, and suppressed hippocampal c-Fos expression during epileptogenesis, suggesting its role in modulating neuronal hyperexcitability (Zhao et al., 2008)