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Immunotherapy The advent of immunotherapy based on immune checkpoint inhibitors (ICIs) targeting programmed cell death protein 1 and its ligands programmed death-ligand 1 and cytotoxic T lymphocyte-associated protein 4 has improved the prognosis of HCC patients

These patches have a defined edge, and occur after injury to the skin, and can usually be seen on the face or hands Treatment Options Chemical peeling, CET, Topical medicine, Whitening Peel,etc Pigmentatio Pedaloides Actinica These freckles may appear after a sunburn caused by UV rays

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