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[DOI] [PubMed] [Google Scholar] 274

Residues were selected based on Chi-specific structural features, including the N-terminal helix, the distinct S-domain, residues forming the hydrophobic pocket (Y177, R226, W255), and the C-terminal helix possibly involved in dimerization

Apo B acts as a major communicator of LDL can spark subendothelial retention of excessive LDL by interacting with ECM components PGs, which is an initial step of atherosclerosis 11,12