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Beyond taxonomic shifts, these microbial changes lead to functional alterations in microbial metabolic activity, resulting in modified production of bioactive metabolites that can influence multiple host physiological systems, including the gutovary axis (73, 74)

Based on these data, we hypothesize that the structured RNA attracts the specific RNA-binding proteins and thus locally increases their concentration, eventually leading to the formation of a condensate in the vicinity of a PIP2-containing surface

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Structure-based development of specific inhibitors for individual cathepsins and their medical applications