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Its so trendy that its a staple of the Paleo diet, bone broth supplements are common, and even bone broth shops exist now

doi: 10.1002/biof.5520170120

This transcription factor also stimulates expression of genes encoding glucose transporters (especially GLUT1), several glycolytic enzymes and lactate dehydrogenase (LDH-A)

The significance of xCT is also linked to its role in GSH production, providing defense against oxidative stress-induced damage and its modulation of mGluRs [39, 72]