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Increased intracellular Ca 2+ activates Ca 2+ -dependent K + channels (Gardos channels), promoting K + efflux and cell shrinkage, while also stimulating scramblases that drive PS externalization (Lang et al., 2003)

A virulent virus is one that causes a disease, and an avirulent virus is one that doesnt cause a disease (some vaccines use avirulent viruses)

This creates a pro-ferroptotic microenvironment for osteoblasts and osteocytes, contributing to abnormal bone remodeling (56)

As our understanding grows, interventions that once seemed counterintuitive (like using pro-oxidants or leveraging glycan signals) may become part of the armamentarium against IBD

The results presented align with earlier studies [21, 41, 67]