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Nevertheless, in contrast to the vast knowledge collected about the detoxification function of GSTs, the understanding of their role in endogenous plant processes and about their metabolic substrates had been still far from complete (Marrs, 1996

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2K), comparable to those in CTX-sensitive Caco-2 ( KRAS WT , HER2 high ) cells, but not in HCT15_shCTRL cells