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High levels of S100A9-positive macrophages in tumors have been correlated with poor patient outcomes in conditions like head and neck cancer and metastatic melanoma, indicating its association with reduced survival rates and diminished response to anti-PD-1 immunotherapy [148]

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Muscle pain, while not the most common side effect, has been reported by some patients

Polymerase chain reaction reveals herpes simplex virus DNA in saliva of patients with behet's disease

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