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After removing the magnetic beads, samples were spun down at 20,000 g for 10 min to remove the remaining beads, and the supernatant was transferred to a scintillation vial with 5 mL of Insta-Gel Plus scintillation cocktail (Perkin Elmer #601339)

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GKT137831 has demonstrated potential in preclinical studies to reduce cardiovascular complications, but current clinical trials on this agent lack evaluation of macrovascular outcomes, highlighting the need for longer-term studies in this setting

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