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This highlights the potential of AI-driven nanoinformatics in addressing treatment complexity and improving patient outcomes (Fig

By contrast, adagrasib has shown both systemic and intracranial antitumor activity, achieving a response rate of ~43% in the KRYSTAL-1 trial (96)

In humans, iron deficiency during perinatal stages results in persistent deficits in learning and memory (reviewed in 60)

[DOI] [PubMed] [Google Scholar] Tavares L.P., Garcia C.C., Vago J.P., Queiroz-Junior C.M., Galvao I., David B.A., Rachid M.A., Silva P.M., Russo R.C., Teixeira M.M., Sousa L.P

Through these mechanisms, GPX4 establishes the redox threshold that separates cell survival from lipid peroxidation-induced death, functioning as the master regulator of ferroptosis