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Munc13-4-deficient mice consequently develop a hemophagocytic-like syndrome with elevated cytokine production, as shown in infected Jinx (Munc13-4-null) mice 56

These features position exosomes as both promising targets for biomarker discovery and effective vehicles for the targeted delivery of therapeutic agents to the central nervous system

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These conditions are largely driven by chronic oxidative stress and inflammation, two factors that glutathione helps combat