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The control group received an equivalent volume of olive oil instead of D-Gal

Furthermore, preclinical studies demonstrated procognitive effects of the H 3 receptor antagonist, ABT-288 (Esbenshade et al., 2012)

It is normal for mast cells to release histamine, but in MCAS theyre hyperactive and release histamine, cytokines, prostaglandins, interleukins, heparin which are all inflammatory