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Compelling findings from germ-free (GF) animal studies have demonstrated that the absence of microbiota leads to substantial neurodevelopmental abnormalities and altered behavior (Sudo et al., 2004

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However, reperfusion can cause further damage to cardiac tissue, including cytokine production, neutrophil infiltration, and ROS production, called I/R injury [89]

Genome sequencing projects were particularly useful for the identification of large numbers of GSTs of unknown function in bacterial and yeast genomes (Vuilleumier and Pagni, 2002