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The advantage of monotherapy extends beyond safety: it simplifies adherence, reduces pill burden, and allows clinicians to titrate one well-understood medication rather than manage interactions between two drug classes

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Unfortunately with small children, the tenting effect that occurs not only brings with it subcutaneous fatty tissue but also a ribbon of muscle that is just as likely, if not more likely to receive the medication that is thought to be being administered into the subcutaneous tissue

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Whilst mild tiredness during the initial weeks of weight loss injection therapy may be expected, certain symptoms warrant prompt medical review