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Experimental Chemicals Iron (III) chloride hexahydrate (FeCl 3 .6H 2 O, 98102%), ethylene glycol ( 99%), urea ( 98%), polyvinylpyrrolidone (PVP) (MW 40,000), acetophenone (99%), sodium pyruvate ( 99%), (s)-methylbenzylamine (s-MBA) ( 98%), pyridoxal 5-phosphate hydrate (PLP) ( 98%), nicotineamide adenine dinucleotide phosphate disodium salt (NADP + ) ( 98%), nitrotetrazolium blue chloride (NBT), phenazine methosulfate (PMS) (90%), d-glucose ( 99.5%) yeast extract, tryptone digest, sodium chloride ( 99.5%), ampicillin sodium salt and phosphate buffered saline (PBS) were all purchased from Sigma Aldrich, UK

Consequently, there is a need to develop rapid and effective neuroprotective therapies for the management of acute ischemic stroke

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As research advances towards more sophisticated, creative therapeutic approaches, manipulating the distinctive metabolism of cancer cells across a targeted variety of AMPK/mTOR pathways provides immense promise for inventing metabolically based therapy strategies that can subdue therapeutic challenges and advance patient outcomes against cancer