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Based on these findings, it is hypothesized that IL-17A inhibitors may improve intestinal inflammation in PSO patients by increasing the abundance of Eubacterium_hallii_group , which promotes SCFA production while increased Parasutterella promotes hypoxanthine production and regulates BAs metabolism in patients, which in turn improves intestinal barrier function and achieves the relief of clinical symptoms

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Comparisons and related research compounds

Accordingly, it scavenges reactive ROS, and regenerate vitamins C and E, and GSH in their active forms (Kucukgoncu et al., 2017)

Non-failing (NF) samples derived from rejected donor hearts were used as controls