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IDR-containing proteins, such as FUS, EWS, and TAF15, accumulate through LLPS at sites of DNA damage in a PAR-dependent manner 130

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Dermatologically tested with a 0.0 skin irritation index,

For crystallographic fragment screening, we soaked 983 fragments from three fragment libraries (the DSiP fragment library 32 , the EUbOPEN DSiP extension library, and the FragLite library 33 ) as singletons into TRF1 TRFH crystal drops

Once there, they inhibit the tyrosinase enzyme, which slows down the production of dark pigment