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Apart from human studies, mice with heterozygous and homozygous mutation in Mthfr C677T still accompany with global DNA hypomethylation, decreased SAM and increased SAH levels 41

6 Discussion and conclusion The skin and mucous membranes of the oral and maxillofacial region are located in exposed areas of the body and are susceptible to interference from internal and external environmental factors, resulting in destruction of the epidermal barrier and the formation of wounds

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10.1080/13510002.2025.2471738 132 Vargas-VargasM.Corts-RojoC

Robert Hendren, University of California San Francisco, USA Copyright 2014 Frye and Rossignol