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10.3390/genes11050579 148

Sugizaki et al

HIF-1 protects the M9a+sh EPAS1 cells against hypoxia-induced apoptosis and inflammation by upregulating mitophagy during hypoxia The role of HIF-1 in regulating mitophagy in M9a+sh EPAS1 cells was examined by treatment with PX-478, a HIF-1 inhibitor (Fig