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If the mitochondrial transport system becomes a bottleneck, if there is not enough carnitine to shuttle all those mobilized fatty acids into the mitochondria for burning, then some of that fat may not get oxidized efficiently

The proapoptotic BCL-2 family of proteins promotes the release of cytochrome c from the mitochondrial intermembrane space into the cytoplasm

Immunolocalization of glutathione reductase in the murine brain

Most studies in this field have tested L-carnitine, and they showed mixed results [77]

Mol Brain 16:116 Zuo X, Zhou J, Li Y et al (2021) TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS