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Oligodendrogenesis in the normal and pathological central nervous system

Our study confirmed important alterations in the oxidative-antioxidative system in patients suffering from SM-induced lung injuries, as shown by a decreased serum level of GSH and an increased level of MDA

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Due to the generally higher metabolic activity in cancer cells and the increased levels of ROS associated with cancer progression, they may be more susceptible to ferroptosis ( 6 MM and ferroptosis 6.1 Lipid metabolism pathway 6.1.1 AA pathway Studies have demonstrated significant reductions in key PUFAs, including ferroptosis-inducing AA, within bone marrow aspirates of MM patients ( Intriguingly, MM plasma cells exhibit elevated GPX4 and xCT levels compared to normal counterparts

Derosa, G., Cicero, A