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To this end, we synthesized a number of per-methylated quinolinium analogues guided by in silico calculation of partition coefficient (c log P)

2 Grip Strength and Exercise Endurance in Aged Mice Dimet-Wiley et al., Scientific Reports (2024) This study compared 5-Amino-1MQ treatment, voluntary wheel-running exercise (PoWeR), and combined treatment in aged C57BL/6J mice

These findings position 5-amino-1MQ as a promising agent for improving regeneration and recovery in skeletal and cardiac muscle tissues