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10.2174/1381612826666200523172334 97 QiuY.GanM.WangX.LiaoT.ChenQ.LeiY.et al (2023)

Lin, S., Cheng, H., Ouyang, Q

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Lactate secreted by CRC cells promotes the polarization of TAMs toward an M2-like immunosuppressive phenotype, impairs CD8 T cell function, and reduces the efficacy of ICIs [126]