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Brenndorfer, E

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Clinical Experience of Proteasome Inhibitor Bortezomib Regarding Efficacy and Safety in Severe Systemic Lupus Erythematosus: A Nationwide Study

This rapid, weight-independent improvement in glucose tolerance suggests that disrupting white fat vasculature directly affects metabolic signaling, possibly by interfering with adipokine production or fatty acid metabolism

In fact, the literature is still too limited to draw firm conclusions on many topics, as it is based primarily on observational evidence and only minimally on interventional studies, with a scarcity of randomized controlled trials