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Researchers initially investigated it as a potential treatment for obesity and metabolic disorders

These pathways were selected because they correspond to the core biological foundations of neurodegenerationproteinopathy, synaptic disfunction, neuroinflammation, mitochondrial impairment, vascular and metabolic dysregulation, among othersthereby anchoring the workflow in mechanisms that are central to dementias and making it applicable across AD, FTD, DLB, vascular and mixed dementias, as well as related neurodegenerative phenotypes that share these pathogenic mechanisms

Blunted stress responses in delayed type hypersensitivity in mice lacking the neuronal isoform of nitric oxide synthase

An electron spin resonance investigation

2.18 Statistical analysis All experiments were conducted in triplicates or quadruplicate across three separate days, each with technical duplicates or triplicates