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High levels of ROS have also been shown to alter the expression patterns of several housekeeping genes, such as FOX3A, NF kappa B, and AP-2

Iwai S, Kikuchi T, Kasahara N, et al

Additionally, aging-related or alcohol-induced downregulation of SIRT1 in neutrophils spurred the acetylation of CCAAT/enhancer-binding protein (C/EBP), controlling miR-223 production