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Treatment of Recurrent Disease After Prior Chemotherapy The efficacy of pemetrexed was evaluated in Study JMEI (NCT00004881), a multicenter, randomized (1:1), open-label study conducted in patients with Stage III or IV NSCLC that had recurred or progressed following one prior chemotherapy regimen for advanced disease

Conclusion: In this large, racially and ethnically diverse EHR-based cohort, the highest HCC risk was seen among NHPI males and females among pre-baby boomers, multiracial males and females in the baby boomers, and Asian American males and females in the post-baby boomers

If symptoms persist beyond 10 days at reduced dose, consider switching injection timing to earlier in the evening (90120 minutes before sleep instead of 3060 minutes) to allow the acute vasodilatory phase to pass before lying down

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

doi: 10.1038/s41586-025-09534-6 37 ButovskyO.WeinerH