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The best time to smoke sativa or indica largely depends on the results you want, and sativas work best when you need mental clarity and motivation

The advice in this country for many years has been if you smoke, you can substantially improve your health by switching to vaping, but if you dont smoke, you shouldnt vape, said Sarah Jackson, principal research fellow at University College Londons Tobacco and Alcohol Research Group

Certain flavouring chemicals, like diacetyl, have also been associated with bronchiolitis obliterans ("popcorn lung"), a serious and irreversible condition

But for small business owners and longtime smokers near the state line, its a price they may not be willing to pay