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doi: 10.1093/genetics/70.2.299 35 LiTCopelandCLeA

Parkin / mice fail to restrict Mtb replication during acute infection, and Smurf / mice display an attenuated capacity to control Mtb infection during the chronic phase, 118,119 suggesting that they have different roles in host anti-Mtb immunity

PMID: 10587285

The CD macrocycle plays a crucial role in hostguest chemistry, enabling the construction of these [4]rotaxanes that appeared to be stable and could be tuned to accommodate different radiometal ion complexes, proteins/peptides, and fluorophores for optical imaging