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Cachn-Vega C, et al

& Stevens, R

However, organotypic brain slice cultures are typically generated using coronal sectioning or regionspecific hippocampal or cerebellar tissue

It is predominantly synthesized from serine through the action of serine hydroxymethyltransferase (SHMT1 and SHMT2), contributing essential one-carbon units to the folate and methionine cycles (117120)