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The data were collected using a Thermo UHPLC-Q Exactive HF-X Mass Spectrometer according to the operating instructions

Therefore, ROS and RNS directly react with numerous biological molecules, leading to tissue toxicity

Methods 9 , 270272 (2012)

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Even in small amounts vitamin C can protect indispensable molecules in the body, such as proteins, lipids (fats), carbohydrates, and nucleic acids (DNA and RNA), from damage by free radicalsand reactive oxygen species (ROS) that are generated during normal metabolism, by active immune cells, and through exposure to toxins and pollutants (e.g., certain chemotherapy drugs and cigarette smoke)