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[1] In living cells, glutathione disulfide is reduced into two molecules of glutathione with reducing equivalents from the coenzyme NADPH

iv) Small molecules targeting the FSP1/CoQ pathway: In addition to erastin, FIN56 is another multimodal inducer of ferroptosis

In rodents, high levels of CDO are expressed in liver and adipose tissue, and both of these tissues also express high levels of CSD and have active taurine biosynthetic pathways (Stipanuk et al