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Furthermore, environmental particulate matter has the ability to cross the blood-brain barrier and penetrate the nasal mucosa epithelium, activating the nervous system by binding to particular receptors and producing oxidative stress (Lucchini et al., 2012)

Brain Sci 13:490 Woods DW, Flessner CA, Franklin ME et al (2006) The trichotillomania impact project (TIP): exploring phenomenology, functional impairment, and treatment utilization

Challenges in topical therapy of chronic rhinosinusitis: the case of nasal drops application a systematic review

Zeng J, Fan J, Zhou H

A doctor at Kursk State Medical University investigated the effects of GSH levels on an individuals ability to recover from COVID-19 infection and found that high ROS/GSH ratios seemed to strongly correlate to worsened symptoms and slower recovery times [72]