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Conceio et al

For example, second and third generation anaplastic lymphoma kinase inhibitors, brigatinib and lorlatinib, respectively, have also been unsuccessful in the treatment of primary brain tumors, despite achieving intracranial responses in the treatment of metastatic non-small cell lung cancer (124)

Segments S5, S6 and extracellular pore loops (P-loops) connecting S5 and S6 in each domain create the pore domain through which Na + ions pass, containing the selectivity filter

Peskin, A

Non-heme iron in humans is located intracellularly in ferritin, but, despite this large iron reserve, most pathogens are unable to scavenge iron from ferritin