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Clinical Intervent Aging 13:757772 Ishihara G, Kawamoto K, Komori N, Ishibashi T (2020) Molecular hydrogen supresses superoxide generation in the mitochondrial complex I and reduced mitochondrial membrane potential

The surplus TMA precursors that cannot be absorbed are converted by gut bacteria into TMA, which is subsequently oxidised by FMO-1 and FMO-3, produced by the liver, to form TMAO

Yu D, Shu XO, Rivera ES, et al

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Finally, two ketothiolase (with a CoA-acyltransferase) generate acetyl CoA and a new acyl-CoA two atoms shorter, which continues through the cycle as far as octanoate, which can then be subjected to mitochondrial -oxidation